Journal of the American Society of Echocardiography
Volume 20, Issue 2 , Pages 136-143 , February 2007

High-resolution Myocardial Perfusion Imaging in Mice with High-frequency Echocardiographic Detection of a Depot Contrast Agent

  • Beat A. Kaufmann, MD

      Affiliations

    • Cardiovascular Divisions at Oregon Health and Sciences University, Portland, Oregon
    • University of Virginia, Charlottesville, Virginia.
    • ,
  • Miles Lankford, BS

      Affiliations

    • University of Virginia, Charlottesville, Virginia.
    • ,
  • Carolyn Z. Behm, MD

      Affiliations

    • University of Virginia, Charlottesville, Virginia.
    • ,
  • Brent A. French, PhD

      Affiliations

    • University of Virginia, Charlottesville, Virginia.
    • ,
  • Alexander L. Klibanov, PhD

      Affiliations

    • University of Virginia, Charlottesville, Virginia.
    • ,
  • Yaqin Xu, MD, PhD

      Affiliations

    • University of Virginia, Charlottesville, Virginia.
    • ,
  • Jonathan R. Lindner, MD, FASE

      Affiliations

    • Cardiovascular Divisions at Oregon Health and Sciences University, Portland, Oregon
    • University of Virginia, Charlottesville, Virginia.
    • Corresponding Author InformationReprint requests: Jonathan R. Lindner, MD, Cardiovascular Division, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Rd, UHN62, Portland, OR 97239

References 

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  12. Lindner JR, Dayton PA, Coggins MP, Ley K, Song J, Ferrara K, et al. Non-invasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. Circulation. 2000;102:531–538
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  17. Lindner JR, Song J, Christiansen J, Klibanov AL, Xu F, Ley K. Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation. 2001;104:2107–2112
  18. Leong-Poi H, Christiansen J, Heppner P, Lewis C, Klibanov A, Kaul S, et al. Assessment of endogenous and therapeutic arteriogenesis by contrast ultrasound molecular imaging of integrin expression. Circulation. 2005;111:3248–3254
  19. Lindner JR, Song J, Jayaweera AR, Sklenar J, Kaul S. Microvascular rheology of Definity microbubbles after intra-arterial and intravenous administration. J Am Soc Echocardiogr. 2002;15:396–403

 Supported by grants to Dr Lindner (R01-HL-074443, R01-HL-078610, and R01-DK-063508) and Dr French (R01-HL-058582 and R01-HL-069494) from the National Institutes of Health, Bethesda, Maryland. Dr Kaufmann is supported by research grants from the Novartis Foundation and the Swiss National Science Foundation. Dr Behm is supported by a Post-doctoral Fellowship Grant from the American Heart Association Mid-Atlantic Affiliate, Baltimore, Maryland.

PII: S0894-7317(06)00817-0

doi: 10.1016/j.echo.2006.08.008

Journal of the American Society of Echocardiography
Volume 20, Issue 2 , Pages 136-143 , February 2007

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