Journal of the American Society of Echocardiography
Volume 21, Issue 1 , Pages 66-71 , January 2008

Prognostic Implications of Relations of Left Ventricular Systolic Dysfunction with Body Composition and Myocardial Energy Expenditure: The Strong Heart Study

  • Vittorio Palmieri, MD, PhD

      Affiliations

    • Weill Medical College of Cornell University, New York, New York
    • ,
  • Mary J. Roman, MD

      Affiliations

    • Weill Medical College of Cornell University, New York, New York
    • ,
  • Jonathan N. Bella, MD

      Affiliations

    • Weill Medical College of Cornell University, New York, New York
    • ,
  • Jennifer E. Liu, MD

      Affiliations

    • Weill Medical College of Cornell University, New York, New York
    • ,
  • Lyle G. Best, MD

      Affiliations

    • Missouri Breaks Industries Research Inc, Timber Lake, South Dakota
    • ,
  • Elisa T. Lee, PhD

      Affiliations

    • University of Oklahoma, Health Sciences Center, Oklahoma City, Oklahoma
    • ,
  • Barbara V. Howard, PhD

      Affiliations

    • MedStar Research Institute, Washington, District of Columbia, Washington, DC.
    • ,
  • Richard B. Devereux, MD

      Affiliations

    • Weill Medical College of Cornell University, New York, New York
    • Corresponding Author InformationReprint requests: Richard B. Devereux, MD, Weill Medical College of Cornell University, 525 E 68 St, Box 222, Room K-415, New York, NY 10021.

References 

  1. Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW. Body-mass index and mortality in a prospective cohort of US adults. N Engl J Med. 1999;341:1097–1105
  2. de Simone G, Wachtell K, Palmieri V, Hille DA, Beevers G, Dahlof B, et al. Body build and risk of cardiovascular events in hypertension and left ventricular hypertrophy: the LIFE (losartan intervention for endpoint reduction in hypertension) study. Circulation. 2005;111:1924–1931
  3. Lavie CJ, Osman AF, Milani RV, Mehra MR. Body composition and prognosis in chronic systolic heart failure: the obesity paradox. Am J Cardiol. 2003;91:891–894
  4. Davos CH, Doehner W, Rauchhaus M, Cicoira M, Francis DP, Coats AJ, et al. Body mass and survival in patients with chronic heart failure without cachexia: the importance of obesity. J Card Fail. 2003;9:29–35
  5. Curtis JP, Selter JG, Wang Y, Rathore SS, Jovin IS, Jadbabaie F, et al. The obesity paradox: body mass index and outcomes in patients with heart failure. Arch Intern Med. 2005;165:55–61
  6. Gustafsson F, Kragelund CB, Torp-Pedersen C, Seibaek M, Burchardt H, Akkan D, et al. Effect of obesity and being overweight on long-term mortality in congestive heart failure: influence of left ventricular systolic function. Eur Heart J. 2005;26:58–64
  7. Anker SD, Chua TP, Ponikowski P, Harrington D, Swan JW, Kox WJ, et al. Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. Circulation. 1997;96:526–534
  8. Starling RD, Toth MJ, Carpenter WH, Matthews DE, Poehlman ET. Energy requirements and physical activity in free-living older women and men: a doubly labeled water study. J Appl Physiol. 1998;85:1063–1069
  9. Devereux RB, Roman MJ, Palmieri V, Liu JE, Lee ET, Best LG, et al. Prognostic implications of ejection fraction from linear echocardiographic dimensions: the Strong Heart Study. Am Heart J. 2003;146:527–534
  10. Hasenfuss G, Mulieri LA, Holubarsch C, Blanchard EM, Just H, Alpert NR. Myocardial adaptation to stress from the viewpoint of adaptation and development. Basic Res Cardiol. 1993;88:91–102
  11. Lee ET, Welty TK, Fabsitz RR, Cowan LD, Le NA, Oopik AJ, et al. The Strong Heart Study–study of cardiovascular disease in American Indians: design and methods. Am J Epidemiol. 1990;132:1141–1155
  12. Welty TK, Lee ET, Yeh J, Cowan LD, Go O, Fabsitz RR, et al. Cardiovascular disease risk factors among American Indians: the Strong Heart Study. Am J Epidemiol. 1995;142:269–287
  13. Howard BV, Lee ET, Cowan LD, Fabsitz RR, Howard WJ, Oopik AJ, et al. Coronary heart disease prevalence and its relation to risk factors in American Indians: the Strong Heart Study. Am J Epidemiol. 1995;142:254–268
  14. Howard BV, Robbins DC, Sievers ML, Lee ET, Rhoades D, Devereux RB, et al. LDL cholesterol as a strong predictor of coronary heart disease in diabetic individuals with insulin resistance and low LDL: the Strong Heart Study. Arterioscler Thromb Vasc Biol. 2000;20:830–835
  15. Howard BV, Lee ET, Cowan LD, Devereux RB, Galloway JM, Go OT, et al. Rising tide of cardiovascular disease in American Indians: the Strong Heart Study. Circulation. 1999;99:2389–2395
  16. Lee ET, Howard BV, Wang W, Welty TK, Galloway JM, Best LG, et al. Prediction of coronary heart disease in a population with high prevalence of diabetes and albuminuria: the Strong Heart Study. Circulation. 2006;113:2897–2905
  17. Devereux RB, Roman MJ, de Simone G, O’Grady MJ, Paranicas M, Yeh JL, et al. Relations of left ventricular mass to demographic and hemodynamic variables in American Indians: the Strong Heart Study. Circulation. 1997;96:1416–1423
  18. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 1997;20:1183–1197
  19. Devereux RB, Roman MJ, Liu JE, Welty TK, Lee ET, Rodeheffer R, et al. Congestive heart failure despite normal left ventricular systolic function in a population-based sample: the Strong Heart Study. Am J Cardiol. 2000;86:1090–1096
  20. Bella JN, Devereux RB, Roman MJ, O’Grady MJ, Welty TK, Lee ET, et al. Relations of left ventricular mass to fat-free and adipose body mass: the Strong Heart Study investigators. Circulation. 1998;98:2538–2544
  21. Zephier EM, Ballew C, Mokdad A, Mendlein J, Smith C, Yeh JL, et al. Intake of nutrients related to cardiovascular disease risk among three groups of American Indians: the Strong Heart dietary Study. Prev Med. 1997;26:508–515
  22. Devereux RB, Roman MJ, Paranicas M, O’Grady MJ, Wood EA, Howard BV, et al. Relations of Doppler stroke volume and its components to left ventricular stroke volume in normotensive and hypertensive American Indians: the Strong Heart Study. Am J Hypertens. 1997;10:619–628
  23. Palmieri V, Dahlöf B, DeQuattro V, Sharpe N, Bella JN, de Simone G, et al. Reliability of echocardiographic assessment of left ventricular structure and function: the PRESERVE study. J Am Coll Cardiol. 1999;34:1625–1632
  24. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18:1440–1463
  25. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986;57:450–458
  26. de Simone G, Daniels SR, Devereux RB, Meyer RA, Roman MJ, de Divitiis O, et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol. 1992;20:1251–1260
  27. Teichholz LE, Kreulen T, Herman MV, Gorlin R. Problems in echocardiographic volume determinations: echocardiographic- angiographic correlations in the presence of absence of asynergy. Am J Cardiol. 1976;37:7–11
  28. Ganau A, Devereux RB, Pickering TG, Roman MJ, Schnall PL, Santucci S, et al. Relation of left ventricular hemodynamic load and contractile performance to left ventricular mass in hypertension. Circulation. 1990;81:25–36
  29. Starling EH, Evans LL. The respiratory exchanges of the heart in the diabetic animal. J Physiol. 1914;49:67
  30. Starling EH, Visscher MB. The regulation of energy output of the heart. J Physiol. 1926;62:243
  31. Bing RJ, Hammond MM, Handelsman JC, Powers SR, Spencer FC, Eckenhoff JE, et al. The measurement of coronary blood flow, oxygen consumption, and efficiency of the left ventricle in man. Am Heart J. 1949;38:1–24
  32. Sarnoff SJ, Braunwald E, Welch GH, Case RB, Stainsby WN, Macruz R. Hemodynamic determinants of oxygen consumption of the heart with special reference to the tension-time index. Am J Physiol. 1958;192:156
  33. Palmieri V, Bella JN, Arnett DK, Oberman A, Kitzman DW, Hopkins PN, et al. Associations of aortic and mitral regurgitation with body composition and myocardial energy expenditure in adults with hypertension: the hypertension genetic epidemiology network study. Am Heart J. 2003;145:1071–1077
  34. Shimizu G, Hirota Y, Kita Y, Kawamura K, Saito T, Gaasch WH. Left ventricular midwall mechanics in systemic arterial hypertension: myocardial function is depressed in pressure-overload hypertrophy. Circulation. 1991;83:1676–1684
  35. Vaz M, Rajkumar C, Wong J, Mazzeo RS, Turner AG, Cox HS, et al. Oxygen consumption in the heart, hepatomesenteric bed, and brain in young and elderly human subjects, and accompanying sympathetic nervous activity. Metabolism. 1996;45:1487–1492
  36. Palmieri V, Tracy RP, Roman MJ, Liu JE, Best LG, Bella JN, et al. Relation of left ventricular hypertrophy to inflammation and albuminuria in adults with type 2 diabetes: the Strong Heart Study. Diabetes Care. 2003;26:2764–2769
  37. Aquilani R, Opasich C, Verri M, Boschi F, Febo O, Pasini E, et al. Is nutritional intake adequate in chronic heart failure patients?. J Am Coll Cardiol. 2003;42:1218–1223
  38. Vaz M, Jennings G, Turner A, Cox H, Lambert G, Esler M. Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation. 1997;96:3423–3429
  39. Leimbach WN, Wallin BG, Victor RG, Aylward PE, Sundlof G, Mark AL. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation. 1986;73:913–919

 Supported by cooperative agreement grants U01-HL41642, HL41652, HL41654, and HL65521 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland, and grant M10RR0047 (General Clinical Research Center) from the National Institutes of Health, Bethesda, Maryland.

PII: S0894-7317(07)00390-2

doi: 10.1016/j.echo.2007.05.008

Journal of the American Society of Echocardiography
Volume 21, Issue 1 , Pages 66-71 , January 2008

Article Tools

* Image Usage & Resolution