Journal of the American Society of Echocardiography
Volume 22, Issue 7 , Pages 766-773, July 2009

Outcomes Research in Cardiovascular Imaging: Report of a Workshop Sponsored by the National Heart, Lung, and Blood Institute

  • Pamela S. Douglas, MD

      Affiliations

    • Division of Cardiovascular Medicine, Duke University Medical Center, Durham, North Carolina
    • Corresponding Author InformationReprint requests and correspondence: Dr. Pamela S. Douglas, 7022 North Pavilion DUMC, P.O. Box 17969, Durham, North Carolina 27715.
    • ,
  • Allen Taylor, MD

      Affiliations

    • Department of Medicine, Cardiovascular Research Institute, Washington Hospital Center, Washington, DC
    • ,
  • Diane Bild, MD

      Affiliations

    • Division of Prevention and Population Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland
    • ,
  • Robert Bonow, MD

      Affiliations

    • Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Philip Greenland, MD

      Affiliations

    • Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Michael Lauer, MD

      Affiliations

    • Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland
    • ,
  • Frank Peacock, MD

      Affiliations

    • Emergency Medicine, Cleveland Clinic, Cleveland, Ohio
    • ,
  • James Udelson, MD

      Affiliations

    • Division of Cardiology, Tufts Medical Center, Boston, Massachusetts

Durham, North Carolina; Washington, DC; Bethesda, Maryland; Chicago, Illinois; Cleveland, Ohio; Boston, Massachusetts

In July of 2008, the National Heart, Lung, and Blood Institute convened experts in noninvasive cardiovascular imaging, outcomes research, statistics, and clinical trials to develop recommendations for future randomized controlled trials of the use of imaging in: 1) screening the asymptomatic patient for coronary artery disease; 2) assessment of patients with stable angina; 3) identification of acute coronary syndromes in the emergency room; and 4) assessment of heart failure patients with chronic coronary artery disease with reduced left ventricular ejection fraction. This study highlights several possible trial designs for each clinical situation.

Key Words: Cardiovascular imaging, Chest pain diagnosis, Clinical trials

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 Dr. Greenland served as a consultant to GE and Toshiba, and received a small honorarium from Pfizer for a role on a Visiting Professor Selection Committee. Dr. Peacock is on the Scientific Advisory Board, or is a consultant or speaker for Abbott, Beckman Coulter, Biosite, Heartscape, Inovise, Inverness, Ortho Clinical Diagnostics, and The Medicine's Company. He has received research grants from Abbott, BAS, Biosite, Brahms, Heartscape, Inovise, Inverness, EKR, and the Medicine's Company. Also, he has an ownership interest in Vital Sensors. Dr. Udelson is co-PI of the ROMICAT-2 trial, sponsored by the American College of Radiology Imaging Network (ACRIN). He has received research funding and has served as a consultant to Lantheus Medical Imaging and Molecular Insight Pharmaceuticals. Drs. Douglas and Taylor are co-first authors. Reviewers for this article are: Stephan Achenbach, MD, Associate Editor, JACC: Cardiovascular Imaging; Thomas Marwick, MBBS, PhD, Associate Editor, JACC: Cardiovascular Imaging; Christopher Kramer, MD, Associate Editor, JACC: Cardiovascular Imaging; Vasken Dilsizian, MD, Associate Editor, JACC: Cardiovascular Imaging.

PII: S0894-7317(09)00532-X

doi:10.1016/j.echo.2009.05.026

Refers to erratum:

  • Erratum

    Journal of the American Society of Echocardiography August 2009 (Vol. 22, Issue 8, Page 882)

Journal of the American Society of Echocardiography
Volume 22, Issue 7 , Pages 766-773, July 2009

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