Journal of the American Society of Echocardiography
Volume 22, Issue 11 , Pages 1296-1301 , November 2009

Left Ventricle to Right Ventricle Size Discrepancy in the Fetus: The Presence of Critical Congenital Heart Disease Can Be Reliably Predicted

  • Michael D. Quartermain, MD

      Affiliations

    • Fetal Heart Program, The Cardiac Center at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • Corresponding Author InformationReprint requests: Michael D. Quartermain, MD, The Children's Hospital of Philadelphia, 34th and Civic Center Boulevard, Division of Cardiology, Main Bldg, 8th Floor, Philadelphia, PA 19104
    • ,
  • Meryl S. Cohen, MD

      Affiliations

    • Fetal Heart Program, The Cardiac Center at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • ,
  • Troy E. Dominguez, MD

      Affiliations

    • Cardiothoracic Unit, Great Ormond Street Hospital for Children, London, United Kingdom
    • ,
  • Zhiyun Tian, MD

      Affiliations

    • Fetal Heart Program, The Cardiac Center at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • ,
  • Denise D. Donaghue, RN, MSN

      Affiliations

    • Fetal Heart Program, The Cardiac Center at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • ,
  • Jack Rychik, MD

      Affiliations

    • Fetal Heart Program, The Cardiac Center at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

References 

  1. Tworetzky W, McElinney DB, Reddy VM, Brook M, Hanley F, Silverman N. Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome. Circulation. 2000;103:1269–1273
  2. Bonnet D, Coltri A, Butera G, Fermont L, Le Bidois J, Kachaner J, et al. Detection of transposition of the great arteries in fetuses reduces neonatal morbidity and mortality. Circulation. 1999;99:916–918
  3. Rudolph AM. Distribution and regulation of blood flow in the fetal and neonatal lamb. Circ Res. 1985;57:811–821
  4. Brown DL, Durfee SM, Hornberger LK. Ventricular size discrepancy as a sonographic sign of coarctation of the fetal aorta: how reliable is it?. J Ultrasound Med. 1997;16:95–99
  5. Sharland GK, Chan KY, Allan LD. Coarctation of the aorta: difficulties in prenatal diagnosis. Br Heart J. 1994;71:70–75
  6. Berning RA, Silverman NH, Villegas M, Sahn DJ, Martin GR, Rice MJ. Reversed shunting across the ductus arteriosus or atrial septum in utero heralds severe congenital heart disease. J Am Coll Cardiol. 1996;27:481–486
  7. Hornberger LK, Sanders SP, Rein A, Spevak PJ, Parness IA, Colan SD. Left heart obstructive Lesions and left ventricular growth in the midtrimester fetus. Circulation. 1995;92:1531–1538
  8. Hornberger LK, Weintraub RG, Pesonen E, Murillo-Olivas A, Simpson IA, Sahn C, et al. Echocardiographic study of the morphology and growth of the aortic arch in the human fetus. Circulation. 1992;86:741–747
  9. Matsui H, Mellander M, Roughton M, Jicinska H, Gardiner H. Morphological and physiological predictors of fetal aortic coarctation. Circulation. 2008;118:1793–1801
  10. Rychik J, Ayres N, Cuneo B, Gotteiner N, Hornberger L, Spevak P, et al. American society of echocardiography guidelines and standards for performance of the fetal echocardiogram. J Am Soc Echocardiogr. 2004;17:803–810
  11. Horton NJ, Lipsitz SR. Review of software to fit generalized estimating equation regression models. Am Statistician. 1999;53:160–169
  12. Feit LR, Copel JA, Kleinman CS. Foramen ovale size in the normal and abnormal human fetal heart: an indicator of transatrial flow physiology. Ultrasound Obstet Gynecol. 1991;1:313–319

PII: S0894-7317(09)00759-7

doi: 10.1016/j.echo.2009.08.008

Journal of the American Society of Echocardiography
Volume 22, Issue 11 , Pages 1296-1301 , November 2009

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