Journal of the American Society of Echocardiography
Volume 23, Issue 1 , Pages 1-8, January 2010

Quantification of Mitral Regurgitation Using High Pulse Repetition Frequency Three-Dimensional Color Doppler

  • Thomas R. Skaug, MD

      Affiliations

    • Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    • Department of Medicine, St Olav's Hospital, Trondheim, Norway
    • Corresponding Author InformationReprint requests: Thomas R. Skaug, MD, Norwegian University of Science and Technology, Department of Circulation and Medical Imaging, 7489 Trondheim, Norway.
    • ,
  • Torbjørn Hergum, MSc

      Affiliations

    • St Olav's Hospital, Trondheim, Norway
    • ,
  • Brage H. Amundsen, MD, PhD

      Affiliations

    • Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    • Department of Cardiology, St Olav's Hospital, Trondheim, Norway
    • ,
  • Terje Skjærpe, MD, PhD

      Affiliations

    • Department of Cardiology, St Olav's Hospital, Trondheim, Norway
    • ,
  • Hans Torp, MSc, Dr Techn

      Affiliations

    • Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    • ,
  • Bjørn Olav Haugen, MD, PhD

      Affiliations

    • Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    • Department of Cardiology, St Olav's Hospital, Trondheim, Norway

published online 16 November 2009.

Background

The aim of this study was to validate a novel method of determining vena contracta area (VCA) and quantifying mitral regurgitation using multibeam high–pulse repetition frequency (HPRF) color Doppler.

Methods

The Doppler signal was isolated from the regurgitant jet, and VCA was found by summing the Doppler power from multiple beams within the vena contracta region, where calibration was done with a reference beam. In 27 patients, regurgitant volume was calculated as the product of VCA and the velocity-time integral of the regurgitant jet, measured by continuous-wave Doppler, and compared with regurgitant volume measured by magnetic resonance imaging (MRI).

Results

Spearman's rank correlation and the 95% limits of agreement between regurgitant volume measured by MRI and by multibeam HPRF color Doppler were rs = 0.82 and −3.0 ± 26.2 mL, respectively.

Conclusion

For moderate to severe mitral regurgitation, there was good agreement between MRI and multibeam HPRF color Doppler. Agreement was lower in mild regurgitation.

Keywords: Mitral regurgitation, Multibeam HPRF color Doppler, PISA, Vena contracta area, Regurgitant volume

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 This study was financed and supported by grants from the Medical Imaging Laboratory for Innovative Future Healthcare, Norwegian University of Science and Technology (Trondheim, Norway), as well as grants from St Olav's University Hospital (Trondheim, Norway) and the Liaison Committee between the Central Norway Regional Health Authority and the Norwegian University of Science and Technology. Dr Torp has served as a scientific advisor for GE Vingmed Ultrasound AS (Horten, Norway).

PII: S0894-7317(09)00910-9

doi:10.1016/j.echo.2009.10.005

Journal of the American Society of Echocardiography
Volume 23, Issue 1 , Pages 1-8, January 2010

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