Journal of the American Society of Echocardiography
Volume 23, Issue 2 , Pages 144-155, February 2010

Patent Foramen Ovale: Echocardiographic Detection and Clinical Relevance in Stroke

  • Marco R. Di Tullio, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Marco R. Di Tullio, MD, Columbia University, College of Physicians & Surgeons, Division of Cardiology, 630 West 168th Street, New York, NY 10032.

Division of Cardiology, Columbia University, New York, NY; and Adult Cardiovascular Ultrasound Laboratories, New York Presbyterian Medical Center, New York, New York

This article reviews the main clinical aspects of patent foramen ovale (PFO), such as its prevalence in the population, the diagnostic techniques to detect its presence, its role as a risk factor for ischemic stroke of otherwise unexplained origin, and its controversial association with migraine. Some cofactors possibly involved in the association between PFO and stroke are discussed, along with the various therapeutic options to prevent recurrent cerebral ischemic events in stroke patients with a PFO.

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PII: S0894-7317(09)01157-2

doi:10.1016/j.echo.2009.12.008

Journal of the American Society of Echocardiography
Volume 23, Issue 2 , Pages 144-155, February 2010