Journal of the American Society of Echocardiography
Volume 23, Issue 5 , Pages 560-566 , May 2010

A Preoperative Echocardiographic Predictive Model for Assessment of Cardiovascular Outcome after Renal Transplantation

  • Qiangjun Cai, MD

      Affiliations

    • Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania
  • ,
  • Ricardo Serrano, MD

      Affiliations

    • Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania
  • ,
  • Arun Kalyanasundaram, MD

      Affiliations

    • Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania
  • ,
  • Jamshid Shirani, MD

      Affiliations

    • Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania
    • Corresponding Author InformationReprint requests: Jamshid Shirani, MD, Department of Cardiology, Geisinger Medical Center, 100 North Academy Ave, Danville, PA 17822.

References 

  1. Kassiske BL, Guijarro C, Massy GA, Wiederkehr MR, Ma JZ. Cardiovascular disease after renal transplantation. J Am Soc Nephrol. 1996;7:158–165
  2. Ojo AO, Hanson JA, Wolfe RA, Leichtman AB, Agodoa LY, Port FK. Long-term survival in renal transplant recipients with graft function. Kidney Int. 2000;57:307–313
  3. Kasiske BL, Cangro CB, Hariharan S, Hricik DE, Kerman RH, Roth D, et al. The evaluation of renal transplantation candidates: clinical practice guidelines. Am J Transplant. 2001;1(Suppl 2):3–95
  4. Marwick TH, Lauer MS, Lobo A, Nally J, Braun W. Use of dobutamine echocardiography for cardiac risk stratification of patients with chronic renal failure. J Intern Med. 1998;244:155–161
  5. Rakhit DJ, Armstrong KA, Beller E, Isbel NM, Marwick TH. Risk stratification of patients with chronic kidney disease: results of screening strategies incorporating clinical risk scoring and dobutamine stress echocardiography. Am Heart J. 2006;152:363–370
  6. Bergeron S, Hillis GS, Haugen EN, Oh JK, Bailey KR, Pellikka PA. Prognostic value of dobutamine stress echocardiography in patients with chronic kidney disease. Am Heart J. 2007;153:385–391
  7. Bart BA, Cen YY, Hendel RC, Lee R, Marwick TH, Missov ED, et al. Comparison of dobutamine stress echocardiography, dobutamine SPECT, and adenosine SPECT myocardial perfusion imaging in patients with end-stage renal disease. J Nucl Cardiol. 2009;16:507–515
  8. Reis G, Marcovitz PA, Leichtman AB, Merion RM, Fay WP, Werns SW, et al. Usefulness of dobutamine stress echocardiography in detecting coronary artery disease in end-stage renal disease. Am J Cardiol. 1995;75:707–710
  9. Bates JR, Sawada SG, Segar DS, Spaedy AJ, Petrovic O, Fineberg NS, et al. Evaluation using dobutamine stress echocardiography in patients with insulin-dependent diabetes mellitus before kidney and/or pancreas transplantation. Am J Cardiol. 1996;77:175–179
  10. Brennan DC, Vedala G, Miller SB, Anstey ME, Singer GG, Kovacs A, et al. Pretransplantation dobutamine stress echocardiography is useful and cost-effective in renal transplant candidates. Transplant Proc. 1997;29:233–234
  11. Herzog CA, Marwick TH, Pheley AM, White CW, Rao VK, Dick CD. Dobutamine stress echocardiography for the detection of significant coronary artery disease in renal transplant candidates. Am J Kidney Dis. 1999;33:1080–1090
  12. West JC, Napoliello DA, Costello JM, Nassef LA, Butcher RJ, Hartle JE, et al. Preoperative dobutamine stress echocardiography versus cardiac arteriography for risk assessment prior to renal transplantation. Transpl Int. 2000;13(Suppl 1):S27–S30
  13. De Lima JJ, Sabbaga E, Vieira ML, de Paula FJ, Ianhez LE, Krieger EM, et al. Coronary angiography is the best predictor of events in renal transplant candidates compared with noninvasive testing. Hypertension. 2003;42:263–268
  14. Sharma R, Pellerin D, Gaze DC, Gregson H, Streather CP, Collinson PO, et al. Dobutamine stress echocardiography and the resting but not exercise electrocardiograph predict severe coronary artery disease in renal transplant candidates. Nephrol Dial Transplant. 2005;20:2207–2214
  15. Sharma R, Pellerin D, Gaze DC, Shah JS, Streather CP, Collinson PO, et al. Dobutamine stress echocardiography and cardiac troponin T for the detection of significant coronary artery disease and predicting outcome in renal transplant candidates. Eur J Echocardiogr. 2005;6:327–335
  16. Gang S, Dabhi M, Rajapurkar MM. Ischaemia imaging in type 2 diabetic kidney transplant candidates—is coronary angiography essential?. Nephrol Dial Transplant. 2007;22:2334–2338
  17. Sharma R, Mehta RL, Brecker SJD, Gaze DC, Gregson H, Streather CP, et al. The diagnostic and prognostic value of tissue Doppler imaging during dobutamine stress echocardiography in end-stage renal disease. Coron Artery Dis. 2009;20:230–237
  18. Dussol B, Bonnet JL, Sampol J, Savin B, De La Forte C, Mundler O, et al. Prognostic value of inducible myocardial ischemia in predicting cardiovascular events after renal transplantation. Kidney Int. 2004;66:1633–1639
  19. Tita C, Karthikeyan V, Store A, Jacobson G, Ananthasubramaniam K. Stress echocardiography for risk stratification in patients with end-stage renal disease undergoing renal transplantation. J Am Soc Echocardiogr. 2008;21:321–326
  20. Lin K, Stewart D, Cooper S, Davis CL. Pre-transplant cardiac testing for kidney-pancreas transplant candidates and association with cardiac outcomes. Clin Transplant. 2001;15:269–275
  21. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986;57:450–458
  22. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296–1305
  23. Parfrey PS, Foley RN. The clinical epidemiology of cardiac disease in chronic renal failure. J Am Soc Nephrol. 1999;10:1606–1615
  24. McCullough PA. Contrast-induced acute kidney injury. J Am Coll Cardiol. 2008;51:1419–1428
  25. Russo D, Corrao S, Miranda I, Ruocco C, Manzi S, Elefante R, et al. Progression of coronary artery calcification in predialysis patients. Am J Nephrol. 2007;27:152–158
  26. Schwarz U, Buzello M, Ritz E, Stein G, Raabe G, Wiest G, et al. Morphology of coronary atherosclerotic lesions in patients with end-stage renal failure. Nephrol Dial Transplant. 2000;15:218–223
  27. Amann K. Media calcification and intima calcification are distinct entities in chronic kidney disease. Clin J Am Soc Nephrol. 2008;3:1599–1605
  28. Schietinger BJ, Brammer GM, Wang H, Christopher JM, Kwon KW, Mangrum AJ, et al. Patterns of late gadolinium enhancement in chronic hemodialysis patients. JACC Cardiovasc Imaging. 2008;1:450–456
  29. Rofsky NM. Nephrogenic systemic fibrosis: considerations for the cardiologist. JACC Cardiovasc Imaging. 2008;1:457–459
  30. Marwick TH, Steinmuller DR, Underwood DA, Hobbs RE, Go RT, Swift C, et al. Ineffectiveness of dipyridamole SPECT thallium imaging as a screening technique for coronary artery disease in patients with end-stage renal failure. Transplantation. 1990;49:100–103
  31. Vandenberg BF, Rossen JD, Grover-McKay M, Shammas NW, Burns TL, Rezai K. Evaluation of diabetic patients for renal and pancreas transplantation: noninvasive screening for coronary artery disease using radionuclide methods. Transplantation. 1996;62:1230–1235
  32. Kasiske BL, Vazquez MA, Harmon WE, Brown RS, Danovitch GM, Gaston RS, et al. Recommendations for the outpatient surveillance of renal transplant recipients. J Am Soc Nephrol. 2000;11(suppl 15):S1–S86
  33. Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LYC, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341:1725–1730
  34. Wali RK, Wang GS, Gottlieb SS, Bellumkonda L, Hansalia R, Ramos E, et al. Effect of kidney transplantation on left ventricular systolic dysfunction and congestive heart failure in patients with end-stage renal disease. J Am Coll Cardiol. 2005;45:1051–1060
  35. Kessler M, Zannad F, Lehert P, Grünfeld JP, Thuilliez C, Leizorovicz A, et al. Predictors of cardiovascular events in patients with end-stage renal disease: an analysis from the Fosinopril in dialysis study. Nephrol Dial Transplant. 2007;22:3573–3579
  36. Sharma R, Chemla E, Tome M, Mehta RL, Gregson H, Brecker S, et al. Echocardiography-based score to predict outcome after renal transplantation. Heart. 2007;93:464–469
  37. Weinrauch LA, D'Elia JA, Monaco AP, Gleason RE, Welty F, Nishan PC, et al. Preoperative evaluation for diabetic renal transplantation: impact of clinical, laboratory, and echocardiographic parameters on patient and allograft survival. Am J Med. 1992;93:19–28
  38. Zoccali C, Benedetto FA, Mallamaci F, Tripepi G, Giacone G, Cataliotti A, et al. Prognostic value of echocardiographic indicators of left ventricular systolic function in asymptomatic dialysis patients. J Am Soc Nephrol. 2004;15:1029–1037
  39. Hayashi SY, Rohani M, Lindholm B, Brodin LA, Lind B, Barany P, et al. Left ventricular function in patients with chronic kidney disease evaluated by colour tissue Doppler velocity imaging. Nephrol Dial Transplant. 2006;21:125–132
  40. Sharma R, Pellerin D, Gaze DC, Mehta RL, Gregson H, Streather CP, et al. Mitral peak Doppler E-wave to peak mitral annulus velocity ratio is an accurate estimate of left ventricular filling pressure and predicts mortality in end-stage renal disease. J Am Soc Echocardiogr. 2006;19:266–273
  41. Hsiao SH, Huang WC, Chiou KR, Lee CY, Yang SH, Wang WC, et al. Major events in uremic patients: insight from parameters derived by flow propagation velocity. J Am Soc Echocardiogr. 2008;21:741–746
  42. Wang AY, Wang M, Lam CW, Chan IH, Zhang Y, Sanderson JE. Left ventricular filling pressure by Doppler echocardiography in patients with end-stage renal disease. Hypertension. 2008;52:107–114
  43. Tripepi G, Benedetto FA, Mallamaci F, Tripepi R, Malatino L, Zoccali C. Left atrial volume monitoring and cardiovascular risk in patients with end-stage renal disease: a prospective cohort study. J Am Soc Nephrol. 2007;18:1316–1322
  44. Barberato SH, Pecoits-Filho R. Usefulness of left atrial volume for the differentiation of normal from pseudonormal diastolic function pattern in patients on hemodialysis. J Am Soc Echocardiogr. 2007;20:359–365
  45. Tripepi G, Mattace-Raso F, Mallamaci F, Benedetto FA, Witteman J, Malatino L, et al. Biomarkers of left atrial volume. A longitudinal study in patients with end stage renal disease. Hyperetension. 2009;54:818–824Epub 2009 Jul 27
  46. Joki N, Hase H, Saijyo T, Tanaka Y, Takahashi Y, Ishikawa H, et al. Combined assessment of cardiac systolic dysfunction and coronary atherosclerosis used to predict future cardiac deaths after starting hemodialysis. Am J Nephrol. 2003;23:458–465
  47. Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS. The cardiovascular HS. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med. 1999;341:142–147
  48. Aronow WS, Ahn C, Shirani J, Kronzon I. Comparison of frequency of new coronary events in older subjects with and without valvular aortic sclerosis. Am J Cardiol. 1999;83:599–600
  49. Chandra HR, Goldstein JA, Choudhary N, O'Neill CS, George PB, Gangasani SR, et al. Adverse outcome in aortic sclerosis is associated with coronary artery disease and inflammation. J Am Coll Cardiol. 2004;43:169–175
  50. Taylor HA, Clark BL, Garrison RJ, Andrew ME, Han H, Fox ER, et al. Relation of aortic valve sclerosis to risk of coronary heart disease in African-Americans. Am J Cardiol. 2005;95:401–404
  51. Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, et al. Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study. J Am Coll Cardiol. 1997;29:630–634
  52. Maher ER, Young G, Smyth-Walsh B, Pugh S, Curtis JR. Aortic and mitral valve calcification in patients with end-stage renal disease. Lancet. 1987;2:875–877
  53. Assal C, Martin B, Serrano R, McConnell T, Shirani J. Coronary atherosclerosis risk assessment using two-dimensional echocardiography. [abstract] Eur J Echocardiographr. 2009;(in press)
  54. Fellström BC, Jardine AG, Schmieder RE, et al. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med. 2009;360:1395–1407
  55. Tripepi G, Benedetto FA, Mallamaci F, Tripepi R, Malatino L, Zoccali C. Left atrial volume monitoring and cardiovascular risk in patients with end-stage renal disease: a prospective cohort study. J Am Soc Nephrol. 2007;18:1316–1322

PII: S0894-7317(10)00228-2

doi: 10.1016/j.echo.2010.03.008

Journal of the American Society of Echocardiography
Volume 23, Issue 5 , Pages 560-566 , May 2010