Journal of the American Society of Echocardiography
Volume 23, Issue 8 , Pages 840-847 , August 2010

Myocardial Contrast Echocardiography Versus Single Photon Emission Computed Tomography for Assessment of Hibernating Myocardium in Ischemic Cardiomyopathy: Preliminary Qualitative and Quantitative Results

References 

  1. Rahimtoola SH. From coronary artery disease to heart failure: role of the hibernating myocardium. Am J Cardiol. 1995;75(suppl):16E–22E
  2. Senior R, Raval U, Lahiri A. Technetium 99m-labelled sestamibi imaging reliably identifies retained contractile reserve in dyssynergic myocardial segments. J Nucl Cardiol. 1995;2:296–302
  3. Kaul S, Force T. Assessment of myocardial perfusion with contrast 2-dimensional echocardiography. In:  Weyman A editors. Principles and practice of echocardiography. Philadelphia, PA: Lea & Febiger; 1993;p. 687–730
  4. Janardhanan R, Swinburn JM, Greaves K, Senior R. Usefulness of myocardial contrast echocardiography using low power continuous imaging early after acute myocardial infarction to predict late functional recovery. Am J Cardiol. 2003;92:492–497
  5. Swinburn JM, Lahiri A, Senior R. Intravenous myocardial echocardiography predicts recovery of dyssynergic myocardium early after acute myocardial infarction. J Am Coll Cardiol. 2001;38:19–25
  6. Janardhanan R, Moon JC, Pennell DJ, Senior R. Myocardial contrast echocardiography accurately reflects transmurality of myocardial necrosis and predicts contractile reserve after acute myocardial infarction. Am Heart J. 2005;149:355–362
  7. Lafitte S, Higashiyama A, Masugata H, Peters B, Strachan M, Kwan OL, et al. Contrast echocardiography can assess risk area and infarct size during coronary occlusion and reperfusion: experimental validation. J Am Coll Cardiol. 2002;39:1546–1554
  8. Coggins MP, Sklenar J, Le DE, Wei K, Lindner JR, Kaul S. Noninvasive prediction of ultimate infarct size at the time of acute coronary occlusion based on the extent and magnitude of collateral-derived myocardial blood flow. Circulation. 2001;104:2471–2477
  9. Shimoni S, Frangogiannis N, Agelli C, Shan L, Verani MS, Quinones MA, et al. Identification of hibernating myocardium with quantitative intravenous myocardial contrast echocardiography. Comparison with dobutamine echocardiography and thallium-201 scintigraphy. Circulation. 2003;107:538–544
  10. Afridi I, Kleiman NS, Raizner AE, Zoghbi WA. Dobutamine echocardiography in myocardial hibernation. Optimal dose and accuracy in predicting recovery of ventricular function after coronary angioplasty. Circulation. 1995;91:663–670
  11. Lieberman AN, Weiss JL, Jugdutt BI, Bulkley LC, Bulkley BH, Garrison JG, et al. Two-dimensional echocardiography and infarct size: relationship of regional wall motion and thickening to the extent myocardial infarction in the dog. Circulation. 1981;63:739–746
  12. Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. AHA Writing Group on Myocardial Segmentation and Registration for Cardiac Imaging. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the cardiac imaging committee of the council on clinical cardiology of the AHA. Circulation. 2002;105:539–542
  13. Vivegnis BTD, Foulon J, Rigo P. Quantitative evaluation of myocardial single-photon emission computed tomographic imaging: application to the measurement of perfusion defect size and severity. Eur J Nucl Med. 1996;23:1603–1612
  14. Senior R, Kaul S, Lahiri A. Myocardial viability on echocardiography predicts long term survival after revascularization in patients with ischemic congestive heart failure. J Am Coll Cardiol. 1999;33:1848–1854
  15. Meluzín J, Cerný J, Frélich M, Stetka F, Spinarová L, Popelová J, et al. Prognostic value of the amount of dysfunctional but viable myocardium in revascularized patients with coronary artery disease and left ventricular dysfunction. J Am Coll Cardiol. 1998;32:912–920
  16. Kassab GS, Lin DH, Fung YB. Topology and dimensions of pig coronary capillary network. Am J Physiol. 1994;267(suppl):H319–H325
  17. Wei K, Firoozan S, Jayaweera AR, Skyba M, Linka A, Kaul S. Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation. 1998;97:473–483
  18. Vogel R, Indermuhle A, Reinhardt J, Meier P, Siegrist PT, Namdar M, et al. The quantification of absolute myocardial perfusion in humans by contrast echocardiography. J Am Coll Cardiol. 2005;45:754–762
  19. Kloner RA, Rude RE, Carlson N, Maroko PR, DeBoer LW, Braunwald E. Ultrastructural evidence of microvascular damage and myocardial cell injury after coronary artery occlusion: which comes first?. Circulation. 1980;62:945–952
  20. Shimoni S, Frangogiannis NG, Agelli CJ, Shan K, Quinones MA, Espada R, et al. Microvascular structural correlates of myocardial contrast echocardiography in patients with coronary artery disease and left ventricular dysfunction. Circulation. 2002;106:950–956
  21. Glover DK, Beller GA, Cunningham M, Edwards NC, Ruiz M, Simanis JP, et al. Comparison between 201Tl and 99mTc sestamibi uptake during adenosine induced vasodilation as a function of coronary artery stenosis severity. Circulation. 1995;91:813–820
  22. Glover DK, Okada RD. Myocardial kinetics of Tc-MIBI in canine myocardium dipyridamole. Circulation. 1990;81:628–637
  23. Nielson AP, Bruno FP, Cobb FR, Morris KG, Murdock R. Linear relationship between the distribution of thallium-201 and blood flow in ischemic and nonischemic myocardium during exercise. Circulation. 1980;61:797–801
  24. Piwnica Worms D, Chiu ML, Kronauge JF. Uptake and retention of hexakis (2-methoxy-isobutyl isonitrile) technetium in cultured chick myocardial cell: mitochondrial and plasma membrane potential. Circulation. 1974;82:391–405
  25. Ragosta M, Beller GA, Watson DD, Kaul S, Gimple LW. Quantitative planar rest-redistribution 201Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function. Circulation. 1993;87:1630–1641
  26. Nagueh SF, Vaduganathan P, Ali N, Blaustein A, Verani MS, Winters WL, et al. Identification of hibernating myocardium: comparative accuracy of myocardial contrast echocardiography, rest-redistribution thallium-201 tomography and dobutamine echocardiography. J Am Coll Cardiol. 1997;29:985–993
  27. Qureshi U, Nagueh SF, Afridi I, Vaduganathan P, Blaustein A, Verani MS, et al. Dobutamine echocardiography and quantitative rest-redistribution 201Tl tomography in myocardial hibernation: relation to contractile reserve to 201Tl uptake and comparative prediction of recovery of function. Circulation. 1997;95:626–635
  28. Senior R, Kaul S, Raval U, Lahiri A. Impact of revascularization and myocardial viability determined by nitrate enhanced tc-99m sestamibi and Tl-201 imaging on mortality and functional outcome in ischemic cardiomyopathy. J Nucl Cardiol. 2002;9:454–462
  29. Mousa SA, Cooney JM, Williams SJ. Relationship between regional myocardial blood flow and the distribution of Tc-99-m-sestamibi in the presence of total coronary artery occlusion. Am Heart J. 1990;119:842
  30. Hayat SA, Dwivedi G, Jacobsen A, Lim TK, Kinsey C, Senior R. Effects of left bundle branch block on cardiac structure, function, perfusion and perfusion reserve. Implications for myocardial contrast echocardiography versus radionuclide perfusion imaging for the detection of coronary artery disease. Circulation. 2008;117:1832–1841
  31. Wei K, Le E, Bin JP, Coggins M, Jayawera , Kaul S. Mechanism of reversible 99mTc-sestamibi perfusion defects during pharmacologically induced coronary vasodilation. Am J Physiol. 2001;280:H1896–H1905
  32. Mor-Avi V, Koch R, Holper EM, Goonewardena S, Coon PD, Min JK, et al. Value of vasodilator stress myocardial contrast echocardiography and magnetic resonance imaging for the differential diagnosis of ischemic versus nonischemic cardiomyopathy. J Am Soc Echocardiogr. 2008;21:425–432
  33. Senior R, Janardhanan R, Jeetley P, Burden L. Myocardial contrast echocardiography for distinguishing ischemic from non-ischemic first-onset acute heart failure: insights into the mechanism of acute heart failure. Circulation. 2005;112:1587–1593

 This work was supported by a grant from the Cardiac Research Fund, Institute of Postgraduate Medical Education and Research (London, United Kingdom).

PII: S0894-7317(10)00476-1

doi: 10.1016/j.echo.2010.06.004

Journal of the American Society of Echocardiography
Volume 23, Issue 8 , Pages 840-847 , August 2010

Article Tools

* Image Usage & Resolution