Two-dimensional echocardiographic calculation of left ventricular mass as recommended by the American Society of Echocardiography: Correlation with autopsy and M-mode echocardiography

Park, Seong H.; Shub, Clarence; Nobrega, Thomas P.; Bailey, Kent R.; Seward, James B.

« Previous Next »Journal of the American Society of Echocardiography
Volume 9, Issue 2 , Pages 119-128, March 1996

Two-dimensional echocardiographic calculation of left ventricular mass as recommended by the American Society of Echocardiography: Correlation with autopsy and M-mode echocardiography

Seong H. Park, MD
- From the Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota, USA
- the Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
- Mayo Foundation, Rochester, Minnesota, USA
Clarence Shub, MD
- Reprint requests: Clarence Shub, MD, Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.
- From the Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota, USA
- the Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
- Mayo Foundation, Rochester, Minnesota, USA
Thomas P. Nobrega, MD
- From the Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota, USA
- the Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
- Mayo Foundation, Rochester, Minnesota, USA
Kent R. Bailey, PhD
- From the Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota, USA
- the Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
- Mayo Foundation, Rochester, Minnesota, USA
James B. Seward, MD
- From the Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota, USA
- the Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
- Mayo Foundation, Rochester, Minnesota, USA

Abstract

The American Society of Echocardiography (ASE) has recommended diastolic area length and truncated ellipsoid methods for estimating left ventricular (LV) mass by two-dimensional (2D) echocardiography. The major goals of this retrospective study were to (1) assess the correlation between ASE-recommended 2D and M-mode echo-derived measurements of LV mass, (2) compare the two ASE-recommended 2D echocardiography methods, and (3) compare the echo-derived LV mass with anatomic LV mass. The study included 2D echocardiograms obtained within 30 days of death from 34 patients who subsequently underwent autopsy and 2D echocardiograms of 56 normal subjects. The formula used for measurement of M-mode echoderived LV mass was LV mass = 0.8 (ASE-cube LV mass) + 0.6 gm. For 2D echo-derived LV mass, the ASE-recommended area length and truncated ellipsoid methods in systole and diastole were used, with and without incorporating the papillary muscles into the myocardial shell. LV mass derived by M-mode echocardiography was comparable to that derived by 2D methods, and it is reasonable to use this technique for normally shaped ventricles. When the papillary muscles were included into the myocardial shell, diastolic 2D methods overestimated autopsy LV mass. Both diastolic area length and truncated ellipsoid methods were comparable to autopsy LV mass. When the papillary muscles were excluded, the systolic area length method showed the best agreement with autopsy LV mass.

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